What Defines Biological Life?

Section Goals

By the end of this section, you will be able to do the following:

  • Formulate a biological definition of “life”
  • Identify and describe the universal characteristics of living things

Scientists believe that the first forms of life on Earth were microorganisms that existed for billions of years in the ocean before plants and animals appeared. The mammals, birds, and flowers so familiar to us are all relatively recent, originating 130 to 250 million years ago. The earliest representatives of the genus Homo, to which we belong, have inhabited this planet for only the last 2.5 million years, and only in the last 300,000 years have humans started looking like we do today .

It’s hard to grasp the vast amounts of time since Earth formed and life first appeared on its surface. It may help to think of Earth’s history as a 24-hour day, as shown in Figure 1. 

 

Illustration of the face of a clock from 1 to 12 and 12 to 1.
Figure 1. “History of Earth in a Day”

What is biology? In simple terms, biology is the study of life. This definition is very broad because the scope of biology is vast. Biologists may study anything from the microscopic or submicroscopic view of a cell to ecosystems and the whole living planet (Figure 2).

 

Photo A depicts round colonies of blue-green algae. Each algae cell is about 5 microns across. Photo B depicts round fossil structures called stromatalites along a watery shoreline.
Figure 2. Formerly called blue-green algae, these (a) cyanobacteria, magnified 300x under a light microscope, are some of Earth’s oldest life forms. These (b) stromatolites along the shores of Lake Thetis in Western Australia are ancient structures formed by layering cyanobacteria in shallow waters. (credit a: modification of work by NASA; credit b: modification of work by Ruth Ellison; scale-bar data from Matt Russell)

Listening to the daily news, you will quickly realize how many aspects of biology we discuss every day. For example, recent news topics include Escherichia coli (Figure 3) outbreaks in spinach and Salmonella contamination in peanut butter. Other subjects include efforts toward finding a cure for AIDS, Alzheimer’s disease, and cancer. On a global scale, many researchers are committed to finding ways to protect the planet, solve environmental issues, and reduce the effects of climate change. All of these diverse endeavors are related to different facets of the discipline of biology.

 

Figure 3. Escherichia coli (E. coli) bacteria, in this scanning electron micrograph, are normal residents of our digestive tracts that aid in absorbing vitamin K and other nutrients. However, virulent strains are sometimes responsible for disease outbreaks.

Biology is the science that studies life, but what exactly is life? This question may sound like a silly question with an obvious response, but it is not always easy to define life. For example, a branch of biology called virology studies viruses, which exhibit some of the characteristics of living entities but lack others. It turns out that although viruses can attack living organisms, cause diseases, and even reproduce, they do not meet the criteria that biologists use to define life. Consequently, virologists are not biologists, strictly speaking. Similarly, some biologists study the early molecular evolution that gave rise to life; since the events that preceded life are not biological events, these scientists are also excluded from biology in the strict sense of the term.

From its earliest beginnings, biology has wrestled with these questions: What are the shared properties that make something “alive”? And once we know something is alive, how do we find meaningful levels of organization in its structure?

All living organisms share several key characteristics or functions: order, sensitivity, or response to the environment, reproduction, growth and development, regulation, homeostasis, and energy processing. When viewed together, these characteristics serve to define life. Each will be described in more detail below.

Order

Photo of a toad
Figure 4. A toad represents a highly organized structure consisting of cells, tissues, organs, and organ systems.

Organisms are highly organized, coordinated structures that consist of one or more cells. Even very simple, single-celled organisms are remarkably complex: inside each cell, atoms make up molecules; these, in turn, make up cell organelles and other cellular inclusions.

In multicellular organisms (Figure 4), similar cells form tissues. Tissues, in turn, collaborate to create organs (body structures with distinct functions). Organs work together to form organ systems.

Sensitivity or Response to Stimuli

Organisms respond to diverse stimuli. For example, plants can bend toward a source of light, climb on fences and walls, or respond to touch (Figure 5). Even tiny bacteria can move toward or away from chemicals (a process called chemotaxis) or light (phototaxis). Movement toward a stimulus is a positive response, while movement away from a stimulus is a negative response.

 

Figure 5. The leaves of this sensitive plant, Mimosa pudica, will instantly droop and fold when touched. After a few minutes, the plant returns to normal. (credit: Alex Lomas)

Watch this video to see how plants respond to a stimulus—from opening to light to wrapping a tendril around a branch to capturing prey.

 

Reproduction

Single-celled organisms reproduce by first duplicating their DNA and then dividing it equally as the cell prepares to divide to form two new cells. Multicellular organisms often produce specialized reproductive germline cells that will form new individuals. When reproduction occurs, DNA containing genes is passed along to an organism’s offspring. These genes ensure that the offspring will belong to the same species and will have similar characteristics, such as size and shape.

Adaptation

All living organisms exhibit a “fit” to their environment. Biologists refer to this fit as adaptation, and it is a consequence of evolution by natural selection, which operates in every lineage of reproducing organisms. Examples of adaptations are diverse and unique, from heat-resistant Archaea that live in boiling hot springs to the tongue length of a nectar-feeding moth that matches the size of the flower from which it feeds. All adaptations enhance the reproductive potential of the individuals exhibiting them, including their ability to survive to reproduce. Adaptations are not constant. As an environment changes, natural selection causes the characteristics of the individuals in a population to track those changes.

Growth and Development

Although no two look alike, these puppies have inherited genes from both parents and share many of the same characteristics.
Figure 6. Although no two look alike, these puppies have inherited genes from both parents and share many of the same characteristics.

Organisms grow and develop following specific instructions coded for by their genes. These genes provide instructions that will direct cellular growth and development, ensuring that a species’ young (Figure 6) will grow up to exhibit many of the same characteristics as its parents.

Regulation

Even the smallest organisms are complex and require multiple regulatory mechanisms to coordinate internal functions, respond to stimuli, and cope with environmental stresses. Two examples of internal functions regulated in an organism are nutrient transport and blood flow. Organs (groups of tissues working together) perform specific functions, such as carrying oxygen throughout the body, removing wastes, delivering nutrients to every cell, and cooling the body.

Homeostasis

Photo of a polar bear
Figure 7. Polar bears (Ursus maritimus) and other mammals living in ice-covered regions maintain their body temperature by
generating heat and reducing heat loss through thick fur and a dense layer of fat under their skin.

In order to function properly, cells need to have appropriate conditions such as proper temperature, pH, and appropriate concentration of diverse chemicals. These conditions may, however, change from one moment to the next. Organisms are able to maintain internal conditions within a narrow range almost constantly, despite environmental changes, through homeostasis (literally, “steady state”)—the ability of an organism to maintain constant internal conditions.

For example, an organism needs to regulate body temperature through a process known as thermoregulation. Organisms that live in cold climates, such as the polar bear (Figure 7), have body structures that help them withstand low temperatures and conserve body heat. Structures that aid in this type of insulation include fur, feathers, blubber, and fat. In hot climates, organisms have methods (such as perspiration in humans or panting in dogs) that help them to shed excess body heat.

Energy Processing

All organisms use a source of energy for their metabolic activities. Some organisms capture energy from the sun and convert it into chemical energy in food (photosynthesis); others use chemical energy in molecules they take in as food (cellular respiration).

Photo of black and white condor in full flight
Figure 8. The California condor (Gymnogyps californianus) uses chemical energy derived from food to power flight. California condors are an endangered species. This bird has a wing tag that helps biologists identify the individual.

Evolution

The diversity of life on Earth is a result of mutations, or random changes, in hereditary material over time. These mutations allow the possibility for organisms to adapt to a changing environment. An organism that evolves characteristics fit for the environment will have greater reproductive success, subject to the forces of natural selection.

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