Vocabulary
- 5α-reductase
-
An enzyme required to convert testosterone to 5α-dihydrotestosterone.
- action potential
-
A transient all-or-nothing electrical current that is conducted down the axon when the membrane potential reaches the threshold of excitation.
- activational effects
-
Physiological and behavioral responses that are reversible and short-lived, occurring in adulthood
- adoption study
-
A behavioral genetic research method that involves the comparison of adopted children to their adoptive and biological parents.
- adult neurogenesis
-
The process in which new neurons are generated in the adult brain.
- affect
-
An emotional process that includes moods, subjective feelings, and discrete emotions.
- affective neuroscience
-
The study of how the brain and nervous system process emotions
- Afferent
-
Signals that travel from the periphery toward the central nervous system and brain, or travel deeper centrally within the brain
- aggregation
-
The stage of neuronal development after migration where different classes of neurons coalesce to form different nervous system structures.
- aggressive behavior
-
A form of social interaction that includes threat, attack, and fighting.
- agonists
-
A drug that increases or enhances a neurotransmitter’s effect
- allele
-
Specific version of a gene
- amygdala
-
Almond-shaped neural structure that is primarily responsible for regulating emotional responses, especially fear.
- amyloid plaques
-
A build-up of misfolded proteins in the brain that play a central role in Alzheimer’s disease
- antagonists
-
A drug that blocks a neurotransmitter’s effect
- anterograde amnesia
-
Inability to create new declarative memories
- anxiety
-
Intense, excessive, and persistent worry and fear about everyday situations. Linked to heightened physical sensations, such as fast heart rate, rapid breathing, sweating, and fatigue
- anxiety disorders
-
A group of disorders that are characterized by excessive and persistent feelings of intense worry, fear, and dread, as well as physical sensations like increased blood pressure and fast heart rate
- Apoptosis
-
The process of programmed cell death to eliminate unwanted cells.
- applied research
-
Research that can be directly applied to an existing problem
- arcuate fasciculus
-
A fiber tract that connects Wernicke’s and Broca’s areas
- associative learning
-
Association of a stimulus with a cue such as with classical Pavlovian conditioning or instrumental conditioning
- autonomic nervous system
-
A part of the peripheral nervous system that connects to glands and smooth muscles. Consists of sympathetic and parasympathetic divisions.
- axon
-
Part of the neuron that extends off the soma, splitting several times to connect with other neurons; main output of the neuron.
- axons
-
A long threadlike part of a neuron that carries electrical impulses away from the cell body and to other neurons
- basal ganglia
-
Subcortical structures of the cerebral hemispheres involved in voluntary movement.
- basic research
-
Also known as pure or fundamental research, seeks to expand scientific knowledge and understand the mechanisms of brain function
- behavioral genetics
-
The empirical science of how genes and environments combine to generate behavior.
- benign tumors
-
Tumors that don't spread to other body parts
- Bipolar disorder and related disorders
-
A type of obsessive-compulsive disorder. Characterized by persistent, intense focus and anxiety over perceived body defects and flaws in appearance
- bipolar disorders
-
Characterized by extreme mood swings from depressive lows to manic highs
- bisexual
-
Attraction to two sexes.
- body dysmorphic disorder
-
A class of psychological disorders; characterized by mania as the defining feature
- brain stem
-
Composed of the medulla oblongata, pons, and the midbrain. The part of the brain that connects the cerebrum to the spinal cord.
- Brainbow
-
A genetic technique in which individual neurons can be labeled and mapped using fluorescent proteins.
- catatonic behaviors
-
Subtype of disorganized or abnormal motor behavior; involves significant reductions in voluntary movement and reduced reactivity to environmental stimulation
- caudate nucleus
-
A “C” shaped subcortical structure located near the thalamus that contributes to the formation of the basal ganglia. There is a caudate nucleus located in each cerebral hemisphere.
- cell membrane
-
A bi-lipid layer of molecules that separates the cell from the surrounding extracellular fluid.
- cell-adhesion molecules
-
A subset of cell surface molecules that are involved in the binding of cells with other cells.
- central nervous system
-
The portion of the nervous system that includes the brain and spinal cord.
- central nucleus
-
Spherical cell group located in the amygdala that is primarily responsible for the bodily reactions associated with fear
- central sulcus
-
The major fissure that divides the frontal and the parietal lobes.
- cerebellum
-
The distinctive structure at the back of the brain between the cerebrum and brainstem. Important for muscle control, such as balance and movement.
- cerebral aqueduct
-
Narrow, 15mm, channel that connects the third ventricle with the fourth ventricle and facilitates the transport of cerebrospinal fluid (CSF).
- cerebral cortex
-
The outermost layer of gray matter of the cerebral hemispheres.
- cerebral hemispheres
-
The cerebral cortex, underlying white matter, and subcortical structures.
- cerebral peduncles
-
Two bundles of nerve fibers that are located in the ventral midbrain and connect the cerebrum to the brain stem.
- cerebral ventricular system
-
Interconnected cavities within the brain tissue that produce and secrete cerebrospinal fluid to protect the brain
- cerebrospinal fluid
-
Cerebrospinal fluid is an ultrafiltrate of plasma that surrounds the brain and spinal cord.
- cerebrum
-
Usually refers to the cerebral cortex and associated white matter, but in some texts includes the subcortical structures.
- chapter
-
a section of a book.
- chromosomal sex
-
The sex of an individual as determined by the sex chromosomes (typically XX or XY) received at the time of fertilization.
- chromosomes
-
a long strand of genetic information
- cingulate cortex
-
A medial cortical brain region that is a part of the limbic system and is Involved in emotion, motivation, learning, and memory.
- consolidation
-
Making a temporary memory more stable and long-lasting
- converging evidence
-
Similar findings reported from multiple studies using different methods.
- corpus callosum
-
Primary bundle of white matter tracts that connect the left and right cerebral hemispheres.
- cortex
-
In neuroanatomy, cortex refers to a thin sheet of neurons
- coup
-
A brain injury that occurs under the site of impact (coup) and on the side opposite the impact due to the brain moving inside the skull (contrecoup)
- Coup and contrecoup
-
A brain injury that occurs under the site of impact (coup) and on the side opposite the impact due to the brain moving inside the skull (contrecoup)
- cranial nerves
-
A set of 12 paired nerves that emerge directly from the brain and relay information between the brain and parts of the body; primarily to the head and neck regions.
- critical periods
-
A special class of sensitive periods in which the effects of experience have lasting consequences on subsequent brain development. Absence of key experiences may lead to a disrupted course of brain development.
- cross-modal plasticity
-
An adaptive process of the brain, such that loss of one sensory modality induces cortical reorganization that leads to enhanced sensory performance in other sensory modalities.
- cytoarchitecture
-
The study of the cellular composition of the central nervous system’s tissues, with a focus on the arrangement, structure, and function of cells.
- Declarative memory
-
Memory that involves remembering events and facts. Also called explicit memory.
- deep brain stimulation
-
implanting electrodes within areas of the brain. The electrodes produce electrical impulses that affect brain activity to treat certain medical conditions.
- delusions
-
False beliefs that are contrary to external reality and are firmly held despite contrary evidence
- demyelination
-
Damage or loss of the myelin sheath surrounding axons in the brain.
- dendrite
-
Part of a neuron that extends away from the cell body and is the main input to the neuron.
- dendrites
-
A branch-like structure of the neuron that extends from the cell body.
- deoxyribonucleic acid (DNA)
-
Helix-shaped molecule made of nucleotide base pairs
- dependent variable
-
The outcome variable that is measured by the researcher. The dependent variable depends on changes of the independent variable.
- depressive disorders
-
A class of mood disorders; marked by a persistent feeling of sadness and loss of interest that causes significant impairments in daily life
- Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR)
-
The current classification system used to diagnose psychological disorders by mental health professionals. Editions of the DSM are typically updated every 5-7 years
- diencephalon
-
Neural structure located deep in the brain that includes the thalamus and hypothalamus. Connects the midbrain to the forebrain.
- diffusion
-
The force on molecules to move from areas of high concentration to areas of low concentration.
- Diffusion Tensor Imaging
-
A variant of Magnetic Resonance Imaging that can non-invasively reveal unique information of white matter microstructures and axonal pathways within the central nervous system.
- disorganized or abnormal motor behavior
-
Prominent feature of Schizophrenia; characterized by extremely disjointed and atypical motor behavior that can cause problems in everyday life, ranging from childlike silliness to unpredictable agitation
- disorganized thinking
-
Prominent feature of Schizophrenia; characterized by a pattern of incoherent and illogical thought processes
- dizygotic twins
-
Twins conceived from two ova and two sperm.
- DNA methylation
-
An epigenetic mechanism wherein a methyl group can tag DNA and activate or repress genes
- dominant allele
-
Allele whose phenotype will be expressed in an individual that possesses that allele
- dopamine
-
Neurotransmitter involved in learning, motivation, and reward. Implicated in schizophrenia
- dopamine hypothesis of schizophrenia
-
An enduring account that suggests a dysregulated dopamine system contributes to symptomatology of schizophrenia; has undergone many iterations
- ectoderm
-
Outermost of the three germ layers in a developing embryo.
- efferent
-
Signals that travel away from the central nervous system or brain to the periphery, such as motor command
- electroconvulsive therapy (ECT)
-
Psychiatric procedure that involves passing electrical currents through the brain to trigger a brief seizure. Effective in treating depression.
- Electroencephalography
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A neuroimaging technique that measures electrical brain activity via multiple electrodes on the scalp.
- electrostatic pressure
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The force on two ions with similar charge to repel each other; the force of two ions with opposite charge to attract to one another.
- embryo
-
A growing organism in the initial stages of development after fertilization.
- empiricism
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A method for acquiring knowledge is one based on observation, including experimentation, rather than a method based only on forms of logical argument or previous authorities.
- encoding
-
The process of initially learning new information
- endocrine gland
-
A ductless gland from which hormones are released into the blood system in response to specific biological signals.
- endoderm
-
Innermost of the three germ layers in a developing embryo.
- endogenous
-
Originating from within an organism. For example, endogenous opioids such as endorphins are produced in the brain.
- engram
-
memory trace, or a hypothetical construct that represents the physical changes in the brain that constitute memory.
- enzyme induction
-
The process by which a drug can enhance the production of an enzyme
- enzymes
-
A protein produced by a living organism that allows or helps a chemical reaction to occur
- epidemiology
-
the branch of medicine that investigates the incidence, causes, and possible control of diseases
- epigenome
-
The genome-wide distribution of epigenetic marks. These marks tell the genome what to do and where and when to do it.
- episodic memories
-
Memory of an autobiographical event (e.g., personal experience)
- excitatory postsynaptic potentials
-
A depolarizing postsynaptic current that causes the membrane potential to become more positive and move towards the threshold of excitation.
- falsifiable
-
A theory or hypothesis is falsifiable (or refutable) if it can be logically contradicted by an empirical test.
- feminization
-
The induction of female traits.
- fissure
-
A deep or large sulcus or valley in the brain
- fissures
- forebrain
-
Also referred to as the prosencephalon. The forward most part of the brain. Consists of the telencephalon and diencephalon.
- frontal cortex
-
The frontal cortex contains four main gyri.
- frontal lobe
-
The front most (anterior) part of the cerebrum; anterior to the central sulcus and responsible for motor output and planning, language, judgment, and decision-making.
- Functional MRI (fMRI)
-
Functional magnetic resonance imaging (fMRI): A neuroimaging technique that infers brain activation by measuring changes in oxygen levels in the blood.
- gap junctions
-
A type of cell junction in which neighboring cells are connected through intercellular channels. Also facilitates the transfer of molecules directly from the cytoplasm of one cell to another cell.
- gender
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The psychological and sociological representations of one’s biological sex.
- gender identity
-
Personal depictions of masculinity and femininity.
- gender role
-
Societal expectations of masculinity and femininity.
- gene expression
-
Gene expression is the process by which the information encoded in a gene is used to direct the assembly of a protein molecule and ultimately affect the phenotype.
- Gene Knock-in
-
A research technique that involves inserting a specific gene in an organism, which allows researchers to study the effect of that gene on the phenotype.
- Gene Knockout
-
A research technique that involves removing or inactivating a specific gene in an organism (often a fruit fly, zebrafish, or mouse), which allows researchers to study the effect of that gene on the phenotype.
- genes
-
A sequence of DNA that controls or partially controls physical characteristics
- genotype
-
Genetic makeup of an individual
- glia cells
-
Non-neuronal cells in the nervous system that play a wide range of supporting roles in the nervous system.
- glial cells
-
Non-neuronal cells that support and insulate neurons. Important for supporting typical brain function and protecting neurons.
- globus pallidus
-
A nucleus of the basal ganglia.
- gonadal sex
-
The sex of an individual as determined by the possession of either ovaries or testes. Females have ovaries, whereas males have testes.
- grandiose delusions
-
Characterized by intense irrational thoughts and fears centered on perceived victimization or belief that one is being persecuted
- gray matter
-
Composes the bark or the cortex of the cerebrum and consists of the cell bodies of the neurons (see also white matter).
- grid cells
-
Specialized cells in the entorhinal cortex that fire at consistent intervals as an animal moves through space. Important for establishing cognitive maps of different environments.
- gyri
-
(plural) Folds between sulci in the cortex.
- gyrus
-
(plural: gyri)
A fold between sulci in the cortex. - habituation
-
Decrease in response after repeated presentation of a stimulus
- hallucination
-
Perceptual experience that emerges in the absence of external stimulation. Extends across different sensory sources (i.e., visual, auditory, tactile, etc.)
- hemispatial neglect
-
Neuropsychological condition in which damage to the parietal lobe impairs attention and awareness of one side of space. Damage to the left hemisphere would lead to neglect of the right visual field.
- hemorrhagic stroke
-
Strokes caused by a ruptured or leaking blood vessel
- heritability coefficient
-
An easily misinterpreted statistical construct that purports to measure the role of genetics in the explanation of differences among individuals.
- heterosexual
-
Opposite-sex attraction.
- heterozygous
-
Consisting of two different alleles
- hindbrain
-
Also referred to as the rhombencephalon. The lower portion of the brain stem. Consists of the metencephalon and myelencephalon.
- hippocampus
-
(plural form, hippocampi)
A nucleus inside (medial) the temporal lobe implicated in learning and memory. - histone modification
-
An epigenetic mechanism in which a chemical group can be attached to a histone to alter the extent to which DNA is wrapped around histones and thereby alters the availability of genes in the DNA and gene expression
- hoarding disorder
-
A type of obsessive-compulsive disorder. Characterized by persistent difficulty in parting with possessions due to a perceived need to save the items
- homosexual
-
Same-sex attraction.
- homozygous
-
Consisting of two identical alleles
- hormones
-
An organic chemical messenger released from endocrine cells that travels through the blood to interact with target cells at some distance to cause a biological response.
- hypothalamus
-
Part of the diencephalon. Regulates biological drives with pituitary gland.
- hypothesis
-
a tentative explanation of some phenomenon that is used as a starting point for further investigation.
- independent variable
-
A variable that is manipulated by the researcher. The independent variable is “independent” of other variables and is typically considered the cause.
- inhibitory postsynaptic potentials
-
A hyperpolarizing postsynaptic current that causes the membrane potential to become more negative and move away from the threshold of excitation.
- insula
-
Region in the cerebral cortex tucked deep into the lateral sulcus. The insula is Involved in many functions and serves as a hub that links large-scale brain systems.
- International Classification of Diseases (ICD-11)
-
A classification system for mental and behavioral disorders used primarily by the World Health Organization to support the global comparison of mortality and morbidity statistics.
- intersex
-
Born with either an absence or some combination of male and female reproductive organs, sex hormones, or sex chromosomes.
- ion channels
-
Proteins that span the cell membrane, forming channels that specific ions can flow through between the intracellular and extracellular space.
- ionotropic receptors
-
Ion channel that opens to allow ions to permeate the cell membrane under specific conditions, such as the presence of a neurotransmitter or a specific membrane potential.
- Ischemic strokes
-
Strokes caused by interruption of blood supply
- Korsakoff’s syndrome
-
A condition of the central nervous system caused by severe deficiency of thiamine (vitamin B-1) that primarily affects the memory system.
- lateral geniculate nucleus (LGN)
-
(or LGN) A nucleus in the thalamus that is innervated by the optic nerves and sends signals to the visual cortex in the occipital lobe.
- lateral prefrontal cortex
-
Part of the prefrontal cortex that supports higher-order functions such as working memory, selective attention, and planning. It is implicated in mood disorders.
- lateral sulcus
-
The major fissure that delineates the temporal lobe below the frontal and the parietal lobes.
- lateralization
-
Refers to the idea that specific functions may reside primarily in one hemisphere or the other (e.g., for the majority of individuals, the left hemisphere is most responsible for language).
- limbic system
-
Involved in learning and emotion. Includes the subcortical structures of the amygdala and hippocampal formation as well as some cortical structures, such as the cingulate cortex. Responsible for aversion and gratification.
- localization of function
-
Different brain functions are processed in or localized to specific brain areas
- long-term depression (LTD)
-
A long lasting decrease in the strength of synaptic connection based on recent patterns of activity.
- long-term memory
-
Memories that have become stabilized over an extended period of time (days, weeks, years).
- long-term potentiation (LTP)
-
A persistent strengthening of synaptic connections based on recent patterns of activity. A mechanism underlying “neurons that fire together, wire together.”
- longitudinal fissure
-
Deep groove that separates the two cerebral hemispheres of the brain.
- Magnetoencephalography (MEG)
-
A brain science technique that measures brain activity by picking up the tiny magnetic fields generated by neural activity.
- malignant tumors
-
Tumors that can spread and invade surrounding tissue
- Mania
-
Prominent feature of bipolar disorder and related disorders; a state of abnormally and persistently excessive enthusiasm and irritable mood
- masculinization
-
The induction of male traits.
- maternal behavior
-
Parental behavior performed by the mother.
- medulla oblongata
-
Extension of the spinal cord that forms the lowest part of the brain stem.
- memory reconsolidation
-
The process in which reactivated memories become transiently sensitive to modifications
- mesencephalon
-
One of the three primary vesicles. Also referred to as the midbrain.
- mesoderm
-
Middle layer of the three germ layers in a developing embryo.
- Metabolism
-
Breakdown of substances
- metencephalon
-
The part of the hindbrain that develops into the cerebellum and pons.
- midbrain
-
Also referred to as the mesencephalon. The top-most portion of the brain stem. Consists of the tectum, the cerebral aqueduct, the tegmentum, and the cerebral peduncles.
- monozygotic twins
-
Twins conceived from a single ovum and a single sperm, therefore genetically identical.
- Mood disorders
-
A class of psychological disorders marked by severe disturbances to emotions and mood
- mutation
-
Sudden, permanent change in a gene
- myelencephalon
-
The part of the hindbrain that develops into the medulla oblongata.
- myelin sheath
-
Substance around the axon of a neuron that serves as insulation to allow the action potential to conduct rapidly toward the terminal buttons.
- necrosis
-
A form of cell injury which results in premature, unprogrammed cell death due to environmental factors such as injury or disease.
- negative symptoms
-
Refer to an absence or reduction of normal behaviors related to motivation and interest, such as social withdrawal, diminished affective response, lack of interest.
- nervous system
-
Complex network of nerves and cells that transmit information between the brain and the rest of the body.
- neural crest
-
A temporary cluster of cells that originate from the side of the neural tube proximal to the epidermal layer. Neural crest cells give rise to diverse cell types that can support many different systems.
- neural diathesis-stress model of schizophrenia
-
Stress, through its effects on cortisol, acts upon a pre-existing vulnerability to trigger or worsen schizophrenia symptoms.
- neural efficiency
-
The process in which the brain spends fewer energy resources to carry out specific brain functions and subsequent behavior. Typically indicative of a matured functional brain network.
- neural folds
-
Ridges of the ectoderm on the neural plate that form around the neural groove and fuse to form the neural tube.
- neural groove
-
Formed when the neural plate folds inward and extends the entire length of the embryo.
- neural proliferation
-
The mass production of cells. Most prominent during early embryonic development.
- neural stem cells
-
Self-renewing cells that ultimately generate neurons or glial cells, which give rise to the entire nervous system.
- neural tube
-
The hollow longitudinal tube formed by the infolding of the neural plate and subsequent fusion of the neural folds. Sets the basis for development of the brain and spinal cord.
- Neurofibrillary tangles
-
abnormal accumulations of a protein called tau that collect inside neurons and is a key biological marker in Alzheimer’s disease
- neurogenesis
-
The process by which new neurons are formed in the brain.
- neuromodulation
-
the process by which neurons use chemical signals (e.g., some neurotransmitters) to bias many neurons, resulting in changes to neuronal properties such as firing activity and synaptic connectivity.
- Neuronal migration
-
The period when neurons migrate from their origin location to their target location. Neuronal Migration brings different classes of neurons together so that they can interact and give rise to various nervous system structures.
- neurons
-
The fundamental units in the brain that transfer information from the brain to the rest of the body.
- neuroplasticity
-
The ability of the brain to reorganize and adapt its activity in response to intrinsic or extrinsic experiences.
- neurotransmitter
-
A chemical substance produced by a neuron that is used for communication between neurons
- neurotransmitters
-
Chemical substance released by the presynaptic terminal button that acts on the postsynaptic cell.
- Non-associative learning
-
Changes in behavior in response to repeated exposure to a stimulus
- nondeclarative memory
-
Memory for information that does not require conscious learning. Includes procedural memory, priming, non-associative learning, and associative learning.
- norepinephrine
-
A neurotransmitter and hormone. Plays an important role in arousal and the “fight-or-flight” response. It is housed primarily in the locus coeruleus.
- nucleus
-
(plural: nuclei)
In neuroanatomy, nucleus or nuclei refers to a cluster of neurons.Collection of nerve cells found in the brain which typically serve a specific function.
- nucleus accumbens
-
A region of the basal forebrain located in front of the preoptic region.
- Obsessive-compulsive and related disorders
-
A group of disorders that center on a cycle of intrusive thoughts, feelings of anxiety, repetitive behaviors, and short-term reliefs.
- occipital lobe
-
The back most (posterior) part of the cerebrum; involved in vision.
- oligodendrocytes
-
glial cells that generate and maintain the myelin sheath
- Optogenetics
-
A biological technique to control the activity of neurons or other cell types with light.
- orbitofrontal cortex
-
A region of the frontal lobes of the brain above the eye sockets.
- organizational effect
-
Early, generally irreversible, effects of steroid hormones that occur during development
- oxytocin
-
A peptide hormone secreted by the pituitary gland to trigger lactation, as well as social bonding.
- paranoid delusions
-
Characterized by intense irrational thoughts and fears centered on perceived victimization or belief that one is being persecuted
- parasympathetic nervous system
-
A division of the autonomic nervous system that is slower than its counterpart—that is, the sympathetic nervous system—and works in opposition to it. Generally engaged in “rest and digest” functions.
- parental behavior
-
Behaviors performed in relation to one’s offspring that contributes directly to the survival of those offspring
- parietal lobe
-
The part of the cerebrum between the frontal and occipital lobes; involved in bodily sensations, visual attention, and integrating the senses.
- parieto-occipital sulcus
-
Deep sulcus that divides the parietal lobe from the occipital lobe.
- paternal care
-
Parental behavior performed by the father or other male.
- periaqueductal gray
-
The gray matter in the midbrain near the cerebral aqueduct.
- peripheral nervous system
-
All of the nerve cells that connect the central nervous system to all the other parts of the body.
- pharmacokinetics
-
The action of a drug through the body, including absorption, distribution, metabolism, and excretion
- phenotype
-
The observable characteristics of an individual
- pituitary gland
-
Small pea-sized gland that produces and secretes hormones as part of the endocrine system. Interacts with the hypothalamus to monitor the regulation of growth, development, and metabolism.
- place cells
-
Specialized cells in the hippocampus that code specific locations in an environment. Important for establishing cognitive maps of different environments
- polygenic
-
Multiple genes affecting a given trait
- polypharmacy
-
The use of many medications
- pons
-
Part of the hindbrain. A bridge that connects the cerebral cortex with the medulla, and reciprocally transfers information back and forth between the brain and the spinal cord.
- Positron Emission Tomography (PET)
-
A neuroimaging technique that measures brain activity by detecting the presence of a radioactive substance in the brain that is initially injected into the bloodstream and then pulled in by active brain tissue.
- post-traumatic stress disorder (PTSD)
-
A psychological disorder that develops in some individuals who have experienced a traumatic event. It is characterized by intense, vivid memories of the traumatic event or related events and intense emotional and physical reactions.
- prefrontal cortex
-
Covers the front part of the frontal lobe of the cerebral cortex. Supports executive functions such as goal-directed behavior, cognitive flexibility, habit formation. Implicated in many psychological disorders
- preoptic area
-
A part of the anterior hypothalamus.
- primary somatosensory cortex (S1)
-
Located on the postcentral gyrus of the parietal lobe; primarily responsible for processing sensory information from the body.
- primary vesicles
-
The three primary vesicles include the prosencephalon (forebrain), mesencephalon (midbrain), and rhombencephalon (hindbrain).
- priming
-
The presentation of one stimulus influences the response to a subsequent stimulus
- procedural memories
-
Type of unconscious memory that allows for remembering procedures and performance of specific tasks
- progesterone
-
A primary progestin that is involved in pregnancy and mating behaviors.
- prolactin
-
A protein hormone that is highly conserved throughout the animal kingdom. It has many biological functions associated with reproduction and synergistic actions with steroid hormones.
- prosencephalon
-
One of the three primary vesicles. Also referred to as the forebrain.
- psychoactive drugs
-
A drug that changes mood or the way someone feels
- psychopathology
-
The scientific study of mental illness or disorders.
- psychotropic drug
-
A drug that changes mood or emotion, usually used when talking about drugs prescribed for various mental conditions (depression, anxiety, schizophrenia, etc.)
- putamen
-
A subcortical structure that contributes to the formation of the basal ganglia. Involved in learning and motor control.
- quantitative genetics
-
Scientific and mathematical methods for inferring genetic and environmental processes based on the degree of genetic and environmental similarity among organisms.
- radial migration
-
The most common mode of neuronal migration in which neurons migrate in a radial pattern to ultimately establish the different layers of the cortex.
- random assignment
-
A way of placing participants into different groups with randomization. Every member of the sample has an equal chance of being placed in a control group or an experimental group.
- receptors
-
A chemical structure on the cell surface or inside of a cell that has an affinity for a specific chemical configuration of a hormone, neurotransmitter, or other compound.
- recessive allele
-
Allele whose phenotype will be expressed only if an individual is homozygous for that allele
- remyelination
-
Regenerative process by which the myelin sheath around a demyelinated axon is restored
- Research Domain Criteria (RDoC)
-
A research framework for investigating mental disorders in terms of varying degrees of dysfunction in psychological and biological systems
- resting membrane potential
-
The voltage inside the cell relative to the voltage outside the cell while the cell is at rest (approximately -70 mV).
- Retrieval
-
The process of accessing stored memories
- retrograde amnesia
-
Inability to retrieve memories from one's past
- rhombencephalon
-
One of the three primary vesicles. Also referred to as the hindbrain.
- Schizophrenia
-
Schizophrenia is a psychological disorder characterized by major disturbances in thought, perception, emotion, and behavior. Major symptoms include hallucinations, delusions, disorganized thinking, abnormal motor behavior, and negative symptoms.
- secondary vesicles
-
The five secondary vesicles include the telencephalon, diencephalon, mesencephalon, metencephalon, and myelencephalon.
- semantic memories
-
Memory of factual information
- sensitive periods
-
Time limited period of development where intrinsic and extrinsic experiences have an especially strong impact on brain development.
- sensitization
-
Increased responsivity after repeated exposure to the same stimulus
- sensory memory
-
Short-term retention of incoming sensory information (e.g., sights, sounds, smells)
- sex
-
A biological descriptor based on reproductive, hormonal, anatomical, and genetic characteristics. Typical sex categories include male, female, and intersex.
- sex determination
-
The point at which an individual begins to develop as either a male or a female. In animals that have sex chromosomes, this occurs at fertilization. Females are XX and males are XY. All eggs bear X chromosomes, whereas sperm can either bear X or Y chromosomes. Thus, it is the males that determine the sex of the offspring.
- sexual differentiation
-
The process by which individuals develop the characteristics associated with being male or female. Differential exposure to gonadal steroids during early development causes sexual differentiation of several structures including the brain.
- sexual fluidity
-
Personal sexual attributes changing due to psychosocial circumstances.
- sexual orientation
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A person’s sexual attraction to other people.
- short-term memory
-
Temporary memory store that holds and processes information for a limited period of time
- sodium-potassium pump
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An ion channel that uses the neuron’s energy (adenosine triphosphate, ATP) to pump three Na+ ions outside the cell in exchange for bringing two K+ ions inside the cell.
- soma
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Cell body of a neuron that contains the nucleus and genetic information and directs protein synthesis.
- somatic delusion
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Characterized by false beliefs that a person’s internal or external bodily functions are abnormal
- somatic nervous system
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A part of the peripheral nervous system that uses cranial and spinal nerves in volitional actions.
- spatial resolution
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A term that refers to how small the elements of an image are; high spatial resolution means the device or technique can resolve very small elements; in neuroscience, it describes how small a structure in the brain can be imaged.
- spinal nerves
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Mixed nerves that carry sensory and motor information between the spinal cord and rest of the body.
- spines
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Protrusions on the dendrite of a neuron that form synapses with terminal buttons of the presynaptic axon.
- stereotaxic unit
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A surgical device that immobilizes an animal’s head and allows precise positioning in an animal’s brain using a three-dimensional coordinate system.
- storage
-
Retention of encoded information
- stria terminalis
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A band of fibers that runs along the top surface of the thalamus.
- structural magnetic resonance imaging
-
A neuroimaging technique that uses the magnetic resonance scanner to create high resolution images of brain structure. The images show brain anatomy, including location, size, and integrity of white and gray matter (but does not reveal brain function or neuronal activity).
- subcortical
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Structures that lie beneath the cerebral cortex, but above the brainstem.
- substantia nigra
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Involved in transferring chemical signals related to reward. Interacts with the basal ganglia to facilitate motor and reward processes.
- subthalamic nucleus
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A small lens-shaped nucleus located within the diencephalon. Interacts with the basal ganglia to facilitate motor regulation.
- sulci
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(plural) Grooves separating folds of the cortex.
- sulcus
-
(plural: sulci)
A groove separating folds of the cortex. - sympathetic nervous system
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A division of the autonomic nervous system, that is faster than its counterpart that is the parasympathetic nervous system and works in opposition to it. Generally engaged in “fight or flight” functions.
- synapse
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The tiny space separating neurons
- synapses
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Specialized junction through which neural signals are transmitted between neurons.
- synaptic gap
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Also known as the synaptic cleft; the small space between the presynaptic terminal button and the postsynaptic dendritic spine, axon, or soma.
- synaptic vesicles
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Groups of neurotransmitters packaged together and located within the terminal button.
- tangential migration
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Another mode of neuronal migration in which neurons migrate tangentially and may emerge as a result of interactions with axons, astrocytes, or independent of interactions with other cells. Does not rely on glial cells for migration.
- target cells
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A cell that has receptors for a specific chemical messenger (hormone or neurotransmitter).
- tectum
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The uppermost part of the midbrain.
- tegmentum
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The ventral portion of the midbrain.
- telencephalon
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Largest portion of the central nervous system and consists of the cerebrum and related structures.
- temporal lobe
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The part of the cerebrum in front of (anterior to) the occipital lobe and below the lateral fissure; involved in vision, auditory processing, memory, and integrating vision and audition.
- temporal resolution
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A term that refers to how small a unit of time can be measured; high temporal resolution means capable of resolving very small units of time; in neuroscience, it describes how precisely in time a process can be measured in the brain.
- terminal button
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The part of the end of the axon that forms synapses with postsynaptic dendrite, axon, or soma.
- testosterone
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The primary androgen secreted by the testes of most vertebrate animals, including men.
- thalamus
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A part of the diencephalon that works as a gateway for incoming and outgoing information.
- theory
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A broad explanation or group of explanations for some aspect of the natural world that is consistently supported by evidence over time
- threshold of excitation
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Specific membrane potential that the neuron must reach to initiate an action potential.
- transcranial direct current stimulation (tDCS)
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A neuroscience technique whereby a weak current is applied to the head that temporarily activates or inhibits ongoing neuronal activity.
- transcranial magnetic stimulation (TMS)
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A neuroscience technique whereby a brief magnetic pulse is applied to the head that temporarily activates or inhibits ongoing neuronal activity.
- transgender man
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A transgender person whose birth sex was female.
- transgender woman
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A transgender person whose birth sex was male.
- twin studies
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A behavior genetic research method that involves a comparison of the similarity of identical (monozygotic; MZ) and fraternal (dizygotic; DZ) twins.
- ventromedial prefrontal cortex
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Part of the prefrontal cortex that is involved in value computation, decision-making, and emotion regulation. Implicated in mood disorders
- visual cortex
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The part of the brain that processes visual information that is located in the back of the brain.
- Wernicke’s area
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A language area in the temporal lobe where linguistic information is comprehended (Also see Broca’s area).
- white matter
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Regions of the nervous system that represent the axons of the nerve cells; whitish in color because of myelination of the nerve cells.
- zygote
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A cell formed by the union of a female gamete (egg) with a male gamete (sperm).