Vocabulary

5α-reductase

An enzyme required to convert testosterone to 5α-dihydrotestosterone.

action potential

A transient all-or-nothing electrical current that is conducted down the axon when the membrane potential reaches the threshold of excitation.

activational effects

Physiological and behavioral responses that are reversible and short-lived, occurring in adulthood

adoption study

A behavioral genetic research method that involves the comparison of adopted children to their adoptive and biological parents.

adult neurogenesis

The process in which new neurons are generated in the adult brain.

affect

An emotional process that includes moods, subjective feelings, and discrete emotions.

affective neuroscience

The study of how the brain and nervous system process emotions

Afferent

Signals that travel from the periphery toward the central nervous system and brain, or travel deeper centrally within the brain

aggregation

The stage of neuronal development after migration where different classes of neurons coalesce to form different nervous system structures.

aggressive behavior

A form of social interaction that includes threat, attack, and fighting.

agonists

A drug that increases or enhances a neurotransmitter’s effect

allele

Specific version of a gene

amygdala

Almond-shaped neural structure that is primarily responsible for regulating emotional responses, especially fear.

amyloid plaques

A build-up of misfolded proteins in the brain that play a central role in Alzheimer’s disease

antagonists

A drug that blocks a neurotransmitter’s effect

anterograde amnesia

Inability to create new declarative memories

anxiety

Intense, excessive, and persistent worry and fear about everyday situations. Linked to heightened physical sensations, such as fast heart rate, rapid breathing, sweating, and fatigue

anxiety disorders

A group of disorders that are characterized by excessive and persistent feelings of intense worry, fear, and dread, as well as physical sensations like increased blood pressure and fast heart rate

Apoptosis

The process of programmed cell death to eliminate unwanted cells.

applied research

Research that can be directly applied to an existing problem

arcuate fasciculus

A fiber tract that connects Wernicke’s and Broca’s areas

associative learning

Association of a stimulus with a cue such as with classical Pavlovian conditioning or instrumental conditioning

autonomic nervous system

A part of the peripheral nervous system that connects to glands and smooth muscles. Consists of sympathetic and parasympathetic divisions.

axon

Part of the neuron that extends off the soma, splitting several times to connect with other neurons; main output of the neuron.

axons

A long threadlike part of a neuron that carries electrical impulses away from the cell body and to other neurons

basal ganglia

Subcortical structures of the cerebral hemispheres involved in voluntary movement.

basic research

Also known as pure or fundamental research, seeks to expand scientific knowledge and understand the mechanisms of brain function

behavioral genetics

The empirical science of how genes and environments combine to generate behavior.

benign tumors

Tumors that don't spread to other body parts

Bipolar disorder and related disorders

A type of obsessive-compulsive disorder. Characterized by persistent, intense focus and anxiety over perceived body defects and flaws in appearance

bipolar disorders

Characterized by extreme mood swings from depressive lows to manic highs

bisexual

Attraction to two sexes.

body dysmorphic disorder

A class of psychological disorders; characterized by mania as the defining feature

brain stem

Composed of the medulla oblongata, pons, and the midbrain. The part of the brain that connects the cerebrum to the spinal cord.

Brainbow

A genetic technique in which individual neurons can be labeled and mapped using fluorescent proteins.

catatonic behaviors

Subtype of disorganized or abnormal motor behavior; involves significant reductions in voluntary movement and reduced reactivity to environmental stimulation

caudate nucleus

A “C” shaped subcortical structure located near the thalamus that contributes to the formation of the basal ganglia. There is a caudate nucleus located in each cerebral hemisphere.

cell membrane

A bi-lipid layer of molecules that separates the cell from the surrounding extracellular fluid.

cell-adhesion molecules

A subset of cell surface molecules that are involved in the binding of cells with other cells.

central nervous system

The portion of the nervous system that includes the brain and spinal cord.

central nucleus

Spherical cell group located in the amygdala that is primarily responsible for the bodily reactions associated with fear

central sulcus

The major fissure that divides the frontal and the parietal lobes.

cerebellum

The distinctive structure at the back of the brain between the cerebrum and brainstem. Important for muscle control, such as balance and movement.

cerebral aqueduct

Narrow, 15mm, channel that connects the third ventricle with the fourth ventricle and facilitates the transport of cerebrospinal fluid (CSF).

cerebral cortex

The outermost layer of gray matter of the cerebral hemispheres.

cerebral hemispheres

The cerebral cortex, underlying white matter, and subcortical structures.

cerebral peduncles

Two bundles of nerve fibers that are located in the ventral midbrain and connect the cerebrum to the brain stem.

cerebral ventricular system

Interconnected cavities within the brain tissue that produce and secrete cerebrospinal fluid to protect the brain

cerebrospinal fluid

Cerebrospinal fluid is an ultrafiltrate of plasma that surrounds the brain and spinal cord.

cerebrum

Usually refers to the cerebral cortex and associated white matter, but in some texts includes the subcortical structures.

chapter

a section of a book.

chromosomal sex

The sex of an individual as determined by the sex chromosomes (typically XX or XY) received at the time of fertilization.

chromosomes

a long strand of genetic information

cingulate cortex

A medial cortical brain region that is a part of the limbic system and is Involved in emotion, motivation, learning, and memory.

consolidation

Making a temporary memory more stable and long-lasting

converging evidence

Similar findings reported from multiple studies using different methods.

corpus callosum

Primary bundle of white matter tracts that connect the left and right cerebral hemispheres.

cortex

In neuroanatomy, cortex refers to a thin sheet of neurons

coup

A brain injury that occurs under the site of impact (coup) and on the side opposite the impact due to the brain moving inside the skull (contrecoup)

Coup and contrecoup

A brain injury that occurs under the site of impact (coup) and on the side opposite the impact due to the brain moving inside the skull (contrecoup)

cranial nerves

A set of 12 paired nerves that emerge directly from the brain and relay information between the brain and parts of the body; primarily to the head and neck regions.

critical periods

A special class of sensitive periods in which the effects of experience have lasting consequences on subsequent brain development. Absence of key experiences may lead to a disrupted course of brain development.

cross-modal plasticity

An adaptive process of the brain, such that loss of one sensory modality induces cortical reorganization that leads to enhanced sensory performance in other sensory modalities.

cytoarchitecture

The study of the cellular composition of the central nervous system’s tissues, with a focus on the arrangement, structure, and function of cells.

Declarative memory

Memory that involves remembering events and facts. Also called explicit memory.

deep brain stimulation

implanting electrodes within areas of the brain. The electrodes produce electrical impulses that affect brain activity to treat certain medical conditions.

delusions

False beliefs that are contrary to external reality and are firmly held despite contrary evidence

demyelination

Damage or loss of the myelin sheath surrounding axons in the brain.

dendrite

Part of a neuron that extends away from the cell body and is the main input to the neuron.

dendrites

A branch-like structure of the neuron that extends from the cell body.

deoxyribonucleic acid (DNA)

Helix-shaped molecule made of nucleotide base pairs

dependent variable

The outcome variable that is measured by the researcher. The dependent variable depends on changes of the independent variable.

depressive disorders

A class of mood disorders; marked by a persistent feeling of sadness and loss of interest that causes significant impairments in daily life

Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR)

The current classification system used to diagnose psychological disorders by mental health professionals. Editions of the DSM are typically updated every 5-7 years

diencephalon

Neural structure located deep in the brain that includes the thalamus and hypothalamus. Connects the midbrain to the forebrain.

diffusion

The force on molecules to move from areas of high concentration to areas of low concentration.

Diffusion Tensor Imaging

A variant of Magnetic Resonance Imaging that can non-invasively reveal unique information of white matter microstructures and axonal pathways within the central nervous system.

disorganized or abnormal motor behavior

Prominent feature of Schizophrenia; characterized by extremely disjointed and atypical motor behavior that can cause problems in everyday life, ranging from childlike silliness to unpredictable agitation

disorganized thinking

Prominent feature of Schizophrenia; characterized by a pattern of incoherent and illogical thought processes

dizygotic twins

Twins conceived from two ova and two sperm.

DNA methylation

An epigenetic mechanism wherein a methyl group can tag DNA and activate or repress genes

dominant allele

Allele whose phenotype will be expressed in an individual that possesses that allele

dopamine

Neurotransmitter involved in learning, motivation, and reward. Implicated in schizophrenia

dopamine hypothesis of schizophrenia

An enduring account that suggests a dysregulated dopamine system contributes to symptomatology of schizophrenia; has undergone many iterations

ectoderm

Outermost of the three germ layers in a developing embryo.

efferent

Signals that travel away from the central nervous system or brain to the periphery, such as motor command

electroconvulsive therapy (ECT)

Psychiatric procedure that involves passing electrical currents through the brain to trigger a brief seizure. Effective in treating depression.

Electroencephalography

A neuroimaging technique that measures electrical brain activity via multiple electrodes on the scalp.

electrostatic pressure

The force on two ions with similar charge to repel each other; the force of two ions with opposite charge to attract to one another.

embryo

A growing organism in the initial stages of development after fertilization.

empiricism

A method for acquiring knowledge is one based on observation, including experimentation, rather than a method based only on forms of logical argument or previous authorities.

encoding

The process of initially learning new information

endocrine gland

A ductless gland from which hormones are released into the blood system in response to specific biological signals.

endoderm

Innermost of the three germ layers in a developing embryo.

endogenous

Originating from within an organism. For example, endogenous opioids such as endorphins are produced in the brain.

engram

memory trace, or a hypothetical construct that represents the physical changes in the brain that constitute memory.

enzyme induction

The process by which a drug can enhance the production of an enzyme

enzymes

A protein produced by a living organism that allows or helps a chemical reaction to occur

epidemiology

the branch of medicine that investigates the incidence, causes, and possible control of diseases

epigenome

The genome-wide distribution of epigenetic marks. These marks tell the genome what to do and where and when to do it.

episodic memories

Memory of an autobiographical event (e.g., personal experience)

excitatory postsynaptic potentials

A depolarizing postsynaptic current that causes the membrane potential to become more positive and move towards the threshold of excitation.

falsifiable

A theory or hypothesis is falsifiable (or refutable) if it can be logically contradicted by an empirical test.

feminization

The induction of female traits.

fissure

A deep or large sulcus or valley in the brain

fissures
forebrain

Also referred to as the prosencephalon. The forward most part of the brain. Consists of the telencephalon and diencephalon.

frontal cortex

The frontal cortex contains four main gyri.

frontal lobe

The front most (anterior) part of the cerebrum; anterior to the central sulcus and responsible for motor output and planning, language, judgment, and decision-making.

Functional MRI (fMRI)

Functional magnetic resonance imaging (fMRI): A neuroimaging technique that infers brain activation by measuring changes in oxygen levels in the blood.

gap junctions

A type of cell junction in which neighboring cells are connected through intercellular channels. Also facilitates the transfer of molecules directly from the cytoplasm of one cell to another cell.

gender

The psychological and sociological representations of one’s biological sex.

gender identity

Personal depictions of masculinity and femininity.

gender role

Societal expectations of masculinity and femininity.

gene expression

Gene expression is the process by which the information encoded in a gene is used to direct the assembly of a protein molecule and ultimately affect the phenotype.

Gene Knock-in

A research technique that involves inserting a specific gene in an organism, which allows researchers to study the effect of that gene on the phenotype.

Gene Knockout

A research technique that involves removing or inactivating a specific gene in an organism (often a fruit fly, zebrafish, or mouse), which allows researchers to study the effect of that gene on the phenotype.

genes

A sequence of DNA that controls or partially controls physical characteristics

genotype

Genetic makeup of an individual

glia cells

Non-neuronal cells in the nervous system that play a wide range of supporting roles in the nervous system.

glial cells

Non-neuronal cells that support and insulate neurons. Important for supporting typical brain function and protecting neurons.

globus pallidus

A nucleus of the basal ganglia.

gonadal sex

The sex of an individual as determined by the possession of either ovaries or testes. Females have ovaries, whereas males have testes.

grandiose delusions

Characterized by intense irrational thoughts and fears centered on perceived victimization or belief that one is being persecuted

gray matter

Composes the bark or the cortex of the cerebrum and consists of the cell bodies of the neurons (see also white matter).

grid cells

Specialized cells in the entorhinal cortex that fire at consistent intervals as an animal moves through space. Important for establishing cognitive maps of different environments.

gyri

(plural) Folds between sulci in the cortex.

gyrus

(plural: gyri)
A fold between sulci in the cortex.

habituation

Decrease in response after repeated presentation of a stimulus

hallucination

Perceptual experience that emerges in the absence of external stimulation. Extends across different sensory sources (i.e., visual, auditory, tactile, etc.)

hemispatial neglect

Neuropsychological condition in which damage to the parietal lobe impairs attention and awareness of one side of space. Damage to the left hemisphere would lead to neglect of the right visual field.

hemorrhagic stroke

Strokes caused by a ruptured or leaking blood vessel

heritability coefficient

An easily misinterpreted statistical construct that purports to measure the role of genetics in the explanation of differences among individuals.

heterosexual

Opposite-sex attraction.

heterozygous

Consisting of two different alleles

hindbrain

Also referred to as the rhombencephalon. The lower portion of the brain stem. Consists of the metencephalon and myelencephalon.

hippocampus

(plural form, hippocampi)
A nucleus inside (medial) the temporal lobe implicated in learning and memory.

histone modification

An epigenetic mechanism in which a chemical group can be attached to a histone to alter the extent to which DNA is wrapped around histones and thereby alters the availability of genes in the DNA and gene expression

hoarding disorder

A type of obsessive-compulsive disorder. Characterized by persistent difficulty in parting with possessions due to a perceived need to save the items

homosexual

Same-sex attraction.

homozygous

Consisting of two identical alleles

hormones

An organic chemical messenger released from endocrine cells that travels through the blood to interact with target cells at some distance to cause a biological response.

hypothalamus

Part of the diencephalon. Regulates biological drives with pituitary gland.

hypothesis

a tentative explanation of some phenomenon that is used as a starting point for further investigation.

independent variable

A variable that is manipulated by the researcher. The independent variable is “independent” of other variables and is typically considered the cause.

inhibitory postsynaptic potentials

A hyperpolarizing postsynaptic current that causes the membrane potential to become more negative and move away from the threshold of excitation.

insula

Region in the cerebral cortex tucked deep into the lateral sulcus. The insula is Involved in many functions and serves as a hub that links large-scale brain systems.

International Classification of Diseases (ICD-11)

A classification system for mental and behavioral disorders used primarily by the World Health Organization to support the global comparison of mortality and morbidity statistics.

intersex

Born with either an absence or some combination of male and female reproductive organs, sex hormones, or sex chromosomes.

ion channels

Proteins that span the cell membrane, forming channels that specific ions can flow through between the intracellular and extracellular space.

ionotropic receptors

Ion channel that opens to allow ions to permeate the cell membrane under specific conditions, such as the presence of a neurotransmitter or a specific membrane potential.

Ischemic strokes

Strokes caused by interruption of blood supply

Korsakoff’s syndrome

A condition of the central nervous system caused by severe deficiency of thiamine (vitamin B-1) that primarily affects the memory system.

lateral geniculate nucleus (LGN)

(or LGN) A nucleus in the thalamus that is innervated by the optic nerves and sends signals to the visual cortex in the occipital lobe.

lateral prefrontal cortex

Part of the prefrontal cortex that supports higher-order functions such as working memory, selective attention, and planning. It is implicated in mood disorders.

lateral sulcus

The major fissure that delineates the temporal lobe below the frontal and the parietal lobes.

lateralization

Refers to the idea that specific functions may reside primarily in one hemisphere or the other (e.g., for the majority of individuals, the left hemisphere is most responsible for language).

limbic system

Involved in learning and emotion. Includes the subcortical structures of the amygdala and hippocampal formation as well as some cortical structures, such as the cingulate cortex. Responsible for aversion and gratification.

localization of function

Different brain functions are processed in or localized to specific brain areas

long-term depression (LTD)

A long lasting decrease in the strength of synaptic connection based on recent patterns of activity.

long-term memory

Memories that have become stabilized over an extended period of time (days, weeks, years).

long-term potentiation (LTP)

A persistent strengthening of synaptic connections based on recent patterns of activity. A mechanism underlying “neurons that fire together, wire together.”

longitudinal fissure

Deep groove that separates the two cerebral hemispheres of the brain.

Magnetoencephalography (MEG)

A brain science technique that measures brain activity by picking up the tiny magnetic fields generated by neural activity.

malignant tumors

Tumors that can spread and invade surrounding tissue

Mania

Prominent feature of bipolar disorder and related disorders; a state of abnormally and persistently excessive enthusiasm and irritable mood

masculinization

The induction of male traits.

maternal behavior

Parental behavior performed by the mother.

medulla oblongata

Extension of the spinal cord that forms the lowest part of the brain stem.

memory reconsolidation

The process in which reactivated memories become transiently sensitive to modifications

mesencephalon

One of the three primary vesicles. Also referred to as the midbrain.

mesoderm

Middle layer of the three germ layers in a developing embryo.

Metabolism

Breakdown of substances

metencephalon

The part of the hindbrain that develops into the cerebellum and pons.

midbrain

Also referred to as the mesencephalon. The top-most portion of the brain stem. Consists of the tectum, the cerebral aqueduct, the tegmentum, and the cerebral peduncles.

monozygotic twins

Twins conceived from a single ovum and a single sperm, therefore genetically identical.

Mood disorders

A class of psychological disorders marked by severe disturbances to emotions and mood

mutation

Sudden, permanent change in a gene

myelencephalon

The part of the hindbrain that develops into the medulla oblongata.

myelin sheath

Substance around the axon of a neuron that serves as insulation to allow the action potential to conduct rapidly toward the terminal buttons.

necrosis

A form of cell injury which results in premature, unprogrammed cell death due to environmental factors such as injury or disease.

negative symptoms

Refer to an absence or reduction of normal behaviors related to motivation and interest, such as social withdrawal, diminished affective response, lack of interest.

nervous system

Complex network of nerves and cells that transmit information between the brain and the rest of the body.

neural crest

A temporary cluster of cells that originate from the side of the neural tube proximal to the epidermal layer. Neural crest cells give rise to diverse cell types that can support many different systems.

neural diathesis-stress model of schizophrenia

Stress, through its effects on cortisol, acts upon a pre-existing vulnerability to trigger or worsen schizophrenia symptoms.

neural efficiency

The process in which the brain spends fewer energy resources to carry out specific brain functions and subsequent behavior. Typically indicative of a matured functional brain network.

neural folds

Ridges of the ectoderm on the neural plate that form around the neural groove and fuse to form the neural tube.

neural groove

Formed when the neural plate folds inward and extends the entire length of the embryo.

neural proliferation

The mass production of cells. Most prominent during early embryonic development.

neural stem cells

Self-renewing cells that ultimately generate neurons or glial cells, which give rise to the entire nervous system.

neural tube

The hollow longitudinal tube formed by the infolding of the neural plate and subsequent fusion of the neural folds. Sets the basis for development of the brain and spinal cord.

Neurofibrillary tangles

abnormal accumulations of a protein called tau that collect inside neurons and is a key biological marker in Alzheimer’s disease

neurogenesis

The process by which new neurons are formed in the brain.

neuromodulation

the process by which neurons use chemical signals (e.g., some neurotransmitters) to bias many neurons, resulting in changes to neuronal properties such as firing activity and synaptic connectivity.

Neuronal migration

The period when neurons migrate from their origin location to their target location. Neuronal Migration brings different classes of neurons together so that they can interact and give rise to various nervous system structures.

neurons

The fundamental units in the brain that transfer information from the brain to the rest of the body.

neuroplasticity

The ability of the brain to reorganize and adapt its activity in response to intrinsic or extrinsic experiences.

neurotransmitter

A chemical substance produced by a neuron that is used for communication between neurons

neurotransmitters

Chemical substance released by the presynaptic terminal button that acts on the postsynaptic cell.

Non-associative learning

Changes in behavior in response to repeated exposure to a stimulus

nondeclarative memory

Memory for information that does not require conscious learning. Includes procedural memory, priming, non-associative learning, and associative learning.

norepinephrine

A neurotransmitter and hormone. Plays an important role in arousal and the “fight-or-flight” response. It is housed primarily in the locus coeruleus.

nucleus

(plural: nuclei)
In neuroanatomy, nucleus or nuclei refers to a cluster of neurons.

Collection of nerve cells found in the brain which typically serve a specific function.

nucleus accumbens

A region of the basal forebrain located in front of the preoptic region.

Obsessive-compulsive and related disorders

A group of disorders that center on a cycle of intrusive thoughts, feelings of anxiety, repetitive behaviors, and short-term reliefs.

occipital lobe

The back most (posterior) part of the cerebrum; involved in vision.

oligodendrocytes

glial cells that generate and maintain the myelin sheath

Optogenetics

A biological technique to control the activity of neurons or other cell types with light.

orbitofrontal cortex

A region of the frontal lobes of the brain above the eye sockets.

organizational effect

Early, generally irreversible, effects of steroid hormones that occur during development

oxytocin

A peptide hormone secreted by the pituitary gland to trigger lactation, as well as social bonding.

paranoid delusions

Characterized by intense irrational thoughts and fears centered on perceived victimization or belief that one is being persecuted

parasympathetic nervous system

A division of the autonomic nervous system that is slower than its counterpart—that is, the sympathetic nervous system—and works in opposition to it. Generally engaged in “rest and digest” functions.

parental behavior

Behaviors performed in relation to one’s offspring that contributes directly to the survival of those offspring

parietal lobe

The part of the cerebrum between the frontal and occipital lobes; involved in bodily sensations, visual attention, and integrating the senses.

parieto-occipital sulcus

Deep sulcus that divides the parietal lobe from the occipital lobe.

paternal care

Parental behavior performed by the father or other male.

periaqueductal gray

The gray matter in the midbrain near the cerebral aqueduct.

peripheral nervous system

All of the nerve cells that connect the central nervous system to all the other parts of the body.

pharmacokinetics

The action of a drug through the body, including absorption, distribution, metabolism, and excretion

phenotype

The observable characteristics of an individual

pituitary gland

Small pea-sized gland that produces and secretes hormones as part of the endocrine system. Interacts with the hypothalamus to monitor the regulation of growth, development, and metabolism.

place cells

Specialized cells in the hippocampus that code specific locations in an environment. Important for establishing cognitive maps of different environments

polygenic

Multiple genes affecting a given trait

polypharmacy

The use of many medications

pons

Part of the hindbrain. A bridge that connects the cerebral cortex with the medulla, and reciprocally transfers information back and forth between the brain and the spinal cord.

Positron Emission Tomography (PET)

A neuroimaging technique that measures brain activity by detecting the presence of a radioactive substance in the brain that is initially injected into the bloodstream and then pulled in by active brain tissue.

post-traumatic stress disorder (PTSD)

A psychological disorder that develops in some individuals who have experienced a traumatic event. It is characterized by intense, vivid memories of the traumatic event or related events and intense emotional and physical reactions.

prefrontal cortex

Covers the front part of the frontal lobe of the cerebral cortex. Supports executive functions such as goal-directed behavior, cognitive flexibility, habit formation. Implicated in many psychological disorders

preoptic area

A part of the anterior hypothalamus.

primary somatosensory cortex (S1)

Located on the postcentral gyrus of the parietal lobe; primarily responsible for processing sensory information from the body.

primary vesicles

The three primary vesicles include the prosencephalon (forebrain), mesencephalon (midbrain), and rhombencephalon (hindbrain).

priming

The presentation of one stimulus influences the response to a subsequent stimulus

procedural memories

Type of unconscious memory that allows for remembering procedures and performance of specific tasks

progesterone

A primary progestin that is involved in pregnancy and mating behaviors.

prolactin

A protein hormone that is highly conserved throughout the animal kingdom. It has many biological functions associated with reproduction and synergistic actions with steroid hormones.

prosencephalon

One of the three primary vesicles. Also referred to as the forebrain.

psychoactive drugs

A drug that changes mood or the way someone feels

psychopathology

The scientific study of mental illness or disorders.

psychotropic drug

A drug that changes mood or emotion, usually used when talking about drugs prescribed for various mental conditions (depression, anxiety, schizophrenia, etc.)

putamen

A subcortical structure that contributes to the formation of the basal ganglia. Involved in learning and motor control.

quantitative genetics

Scientific and mathematical methods for inferring genetic and environmental processes based on the degree of genetic and environmental similarity among organisms.

radial migration

The most common mode of neuronal migration in which neurons migrate in a radial pattern to ultimately establish the different layers of the cortex.

random assignment

A way of placing participants into different groups with randomization. Every member of the sample has an equal chance of being placed in a control group or an experimental group.

receptors

A chemical structure on the cell surface or inside of a cell that has an affinity for a specific chemical configuration of a hormone, neurotransmitter, or other compound.

recessive allele

Allele whose phenotype will be expressed only if an individual is homozygous for that allele

remyelination

Regenerative process by which the myelin sheath around a demyelinated axon is restored

Research Domain Criteria (RDoC)

A research framework for investigating mental disorders in terms of varying degrees of dysfunction in psychological and biological systems

resting membrane potential

The voltage inside the cell relative to the voltage outside the cell while the cell is at rest (approximately -70 mV).

Retrieval

The process of accessing stored memories

retrograde amnesia

Inability to retrieve memories from one's past

rhombencephalon

One of the three primary vesicles. Also referred to as the hindbrain.

Schizophrenia

Schizophrenia is a psychological disorder characterized by major disturbances in thought, perception, emotion, and behavior. Major symptoms include hallucinations, delusions, disorganized thinking, abnormal motor behavior, and negative symptoms.

secondary vesicles

The five secondary vesicles include the telencephalon, diencephalon, mesencephalon, metencephalon, and myelencephalon.

semantic memories

Memory of factual information

sensitive periods

Time limited period of development where intrinsic and extrinsic experiences have an especially strong impact on brain development.

sensitization

Increased responsivity after repeated exposure to the same stimulus

sensory memory

Short-term retention of incoming sensory information (e.g., sights, sounds, smells)

sex

A biological descriptor based on reproductive, hormonal, anatomical, and genetic characteristics. Typical sex categories include male, female, and intersex.

sex determination

The point at which an individual begins to develop as either a male or a female. In animals that have sex chromosomes, this occurs at fertilization. Females are XX and males are XY. All eggs bear X chromosomes, whereas sperm can either bear X or Y chromosomes. Thus, it is the males that determine the sex of the offspring.

sexual differentiation

The process by which individuals develop the characteristics associated with being male or female. Differential exposure to gonadal steroids during early development causes sexual differentiation of several structures including the brain.

sexual fluidity

Personal sexual attributes changing due to psychosocial circumstances.

sexual orientation

A person’s sexual attraction to other people.

short-term memory

Temporary memory store that holds and processes information for a limited period of time

sodium-potassium pump

An ion channel that uses the neuron’s energy (adenosine triphosphate, ATP) to pump three Na+ ions outside the cell in exchange for bringing two K+ ions inside the cell.

soma

Cell body of a neuron that contains the nucleus and genetic information and directs protein synthesis.

somatic delusion

Characterized by false beliefs that a person’s internal or external bodily functions are abnormal

somatic nervous system

A part of the peripheral nervous system that uses cranial and spinal nerves in volitional actions.

spatial resolution

A term that refers to how small the elements of an image are; high spatial resolution means the device or technique can resolve very small elements; in neuroscience, it describes how small a structure in the brain can be imaged.

spinal nerves

Mixed nerves that carry sensory and motor information between the spinal cord and rest of the body.

spines

Protrusions on the dendrite of a neuron that form synapses with terminal buttons of the presynaptic axon.

stereotaxic unit

A surgical device that immobilizes an animal’s head and allows precise positioning in an animal’s brain using a three-dimensional coordinate system.

storage

Retention of encoded information

stria terminalis

A band of fibers that runs along the top surface of the thalamus.

structural magnetic resonance imaging

A neuroimaging technique that uses the magnetic resonance scanner to create high resolution images of brain structure. The images show brain anatomy, including location, size, and integrity of white and gray matter (but does not reveal brain function or neuronal activity).

subcortical

Structures that lie beneath the cerebral cortex, but above the brainstem.

substantia nigra

Involved in transferring chemical signals related to reward. Interacts with the basal ganglia to facilitate motor and reward processes.

subthalamic nucleus

A small lens-shaped nucleus located within the diencephalon. Interacts with the basal ganglia to facilitate motor regulation.

sulci

(plural) Grooves separating folds of the cortex.

sulcus

(plural: sulci)
A groove separating folds of the cortex.

sympathetic nervous system

A division of the autonomic nervous system, that is faster than its counterpart that is the parasympathetic nervous system and works in opposition to it. Generally engaged in “fight or flight” functions.

synapse

The tiny space separating neurons

synapses

Specialized junction through which neural signals are transmitted between neurons.

synaptic gap

Also known as the synaptic cleft; the small space between the presynaptic terminal button and the postsynaptic dendritic spine, axon, or soma.

synaptic vesicles

Groups of neurotransmitters packaged together and located within the terminal button.

tangential migration

Another mode of neuronal migration in which neurons migrate tangentially and may emerge as a result of interactions with axons, astrocytes, or independent of interactions with other cells. Does not rely on glial cells for migration.

target cells

A cell that has receptors for a specific chemical messenger (hormone or neurotransmitter).

tectum

The uppermost part of the midbrain.

tegmentum

The ventral portion of the midbrain.

telencephalon

Largest portion of the central nervous system and consists of the cerebrum and related structures.

temporal lobe

The part of the cerebrum in front of (anterior to) the occipital lobe and below the lateral fissure; involved in vision, auditory processing, memory, and integrating vision and audition.

temporal resolution

A term that refers to how small a unit of time can be measured; high temporal resolution means capable of resolving very small units of time; in neuroscience, it describes how precisely in time a process can be measured in the brain.

terminal button

The part of the end of the axon that forms synapses with postsynaptic dendrite, axon, or soma.

testosterone

The primary androgen secreted by the testes of most vertebrate animals, including men.

thalamus

A part of the diencephalon that works as a gateway for incoming and outgoing information.

theory

A broad explanation or group of explanations for some aspect of the natural world that is consistently supported by evidence over time

threshold of excitation

Specific membrane potential that the neuron must reach to initiate an action potential.

transcranial direct current stimulation (tDCS)

A neuroscience technique whereby a weak current is applied to the head that temporarily activates or inhibits ongoing neuronal activity.

transcranial magnetic stimulation (TMS)

A neuroscience technique whereby a brief magnetic pulse is applied to the head that temporarily activates or inhibits ongoing neuronal activity.

transgender man

A transgender person whose birth sex was female.

transgender woman

A transgender person whose birth sex was male.

twin studies

A behavior genetic research method that involves a comparison of the similarity of identical (monozygotic; MZ) and fraternal (dizygotic; DZ) twins.

ventromedial prefrontal cortex

Part of the prefrontal cortex that is involved in value computation, decision-making, and emotion regulation. Implicated in mood disorders

visual cortex

The part of the brain that processes visual information that is located in the back of the brain.

Wernicke’s area

A language area in the temporal lobe where linguistic information is comprehended (Also see Broca’s area).

white matter

Regions of the nervous system that represent the axons of the nerve cells; whitish in color because of myelination of the nerve cells.

zygote

A cell formed by the union of a female gamete (egg) with a male gamete (sperm).

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Biological Psychology [Revised Edition] Copyright © 2024 by Michael J. Hove and Steven A. Martinez is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, except where otherwise noted.

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